https://www.selleckchem.com/pr....oducts/oxythiamine-c
Activation of the innate immune system may play a role in the development of alcohol use disorders (AUDs), which often originate with adolescent alcohol abuse. A key player in the innate immune system is microglia, the activation of which occurs along a spectrum from proinflammatory, or M1-like, to anti-inflammatory, or M2-like, phenotypes. Adolescent, male rats were gavaged with ethanol (EtOH) or isocaloric control diet every 8hours for 4days and then sacrificed at 0, 2, 7, and 14days later. Microglia were is