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In combination with acoustic droplet dispensing, referred to as acoustic ejection mass spectrometry (AEMS), this system can be considered to be a special case of flow injection analysis with unique features that control the peak width, symmetry, and segregation of the samples transported in a fluid while simultaneously enabling their mixing and dilution with carrier fluids. In addition, conditions are established to prevent direct contact of the sample with a surface enabling, in combination with a contact-free dispenser like acoustic ej