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Aim To elicit patients' preferences for HIV treatment of the rural population in Colombia.Methods A discrete choice experiment (DCE), conducted in a HIV clinic in Bogotá, was used to examine the trade-off between five HIV treatment attributes effect on life expectancy, effect on physical activity, risk of moderate side effects, accessibility to clinic and economic costs to access controls. Attributes selection was based on literature review, expert consultation and a focus group with six patients. An efficient experimental design was used