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ADHD Treatment For Adults The stimulants methylphenidate and amphetamine can boost the levels of certain brain chemicals. Non-stimulants such as atomoxetine and antidepressants work slower than stimulants, but they could be just as beneficial. Complicating conditions often influence the response to ADHD medications. Doctors should treat the most severe symptoms of any comorbid disorder first, then examine whether the ADHD symptoms improve. Medication Medication is the most