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05). ATP content, citrate synthase activities of gastrocnemius were robustly elevated in LHTL and LLTH groups (p 0.01). The exercise training increased Mff protein and ATP content in gastrocnemius as well as VEGF expression in quadriceps (p 0.05). The hypoxic exposure also increased ATP content, citrate synthase, and ATP synthase activities in gastrocnemius as well as VEGF expression in quadriceps (p 0.01). Our results suggested that hypoxic trainings, especially LLTH, promoted mitochondrial turnover and angiogenesis of s