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We investigated the specific anti-viral T-cell reaction in SLE patients with CMV infection and its own feasible impacts on medical manifestations in lupus. TECHNIQUES CD28 null T-cell percentages had been assessed by flow cytometry in 89 SLE patients and 58 healthy settings. A specific anti-CMV CD8 T-cell response had been assessed ex vivo because of the creation of intracellular cytokines as a result to CMV phosphoprotein 65 (pp65) by movement cytometry. Medica