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Patients receiving cardiac surgery are susceptible to anemia. Low hemoglobin concentration is a risk factor for composite adverse events and mortality after cardiac surgery. Here we investigated the association of postoperative nadir hemoglobin with adverse outcomes in patients undergoing on-pump cardiac surgery. Adult patients in two medical centers were retrospectively analyzed. Primary outcome was postoperative composite adverse event. Secondary outcome was all-cause mortality in hospital. Of the 8206 patients analyzed, 1628 (19.8%) experienced c