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The dopaminergic lesions when you look at the GP would not influence sucrose inclination, personal communication or ambulation. These results reveal that dopamine when you look at the GP, acting through D2 or D4 receptors, could be involved in the manifestation of anxiety, a non-motor manifestation of PD that often appears before engine signs. The goal of this research would be to explore the neurobiological background of specific susceptibility and opposition towards the