https://www.selleckchem.com/pr....oducts/pf-3758309.ht
Rather than being confined to a small number of distal elements or promoters, we find that genetic signals converge on congruently regulated sets of DHSs that decorate entire gene bodies. Together, our results create a universal, extensible coordinate system and vocabulary for human regulatory DNA marked by DHSs, and provide a new global perspective on the architecture of human gene regulation.The majority of therapies that target individual proteins rely on specific activity-modulating interactions with the target protein-for exampl
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