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Sharp injuries are common reasons for the transmission of blood-borne diseases in acute care settings. Fear of sharp injuries and their consequences can expose nurses to high levels of stress (sharp injuries stress). To examine the occurrence of sharp injuries and to assess their relationship with stress among nurses working in acute care settings. This was a cross-sectional study. A total of 150 nurses working in 10 acute care settings in two selected hospitals in Alexandria, Egypt, were selected as the population of this study. Data