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till have a positive effect on immunological function of patients undergoing esophagectomy. Immunonutrition is a safe and feasible nutritional treatment, which has a positive modulatory impact on immune responses after esophagectomy. Although no significant difference was found in clinical and survival outcomes between EIN and EN groups, immunonutrition could still have a positive effect on immunological function of patients undergoing esophagectomy. Cancer patients are vulnerable to the coronavirus disease (COVID-19) given their compro