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Based on the porous internal structure, we also demonstrate some potential applications of the hydrogels for assembly of nanomaterials, such as Au nanorods for remote sensing system and model protein of insulin for drug controlled release. Moreover, the process proved to be versatile, allowing the use of most natural polymer including gelatin, alginate, and so on. Thus, coupling of such straightforward fabrication approach, multifunctionality and biodegradable prerequisite feature indicates great potential for use in the minimally inva