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8% vs 7.2%, P less then 0.001). However, there was no significant difference between patients without using FA and subjects using middle dose of FA (7.2% vs 5.6%, p = 0.355). Multivariate logistic regression analysis showed that low dose of FA was a protective factor for postoperative AKI (OR = 0.75, p = 0.0188), and large dose of FA was a risk factor for postoperative AKI (OR = 4.8, p less then 0.0001). CONCLUSIONS The impact of FA on postoperative AKI was dose-dependent, using of low dose FA (50-100 mg) perioperatively may effec