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Our study provides novel insights into the possible pathway underlying the response of bacterium to environmental stress for phenol degradation.A human health risk assessment (HHRA) will not remain simple and straightforward when it involves multiple uncertain input variables. Uncertainties in HHRA result from the unavailability and subjectivity of input variables. Though several studies have performed HHRA, the quantification of uncertainty in HHRA under a situation of data scarcity and the simultaneous application of random and non-ran