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The development and increase of media literacy can also increase health literacy. We evaluated unmet needs of lower urinary tract symptoms-benign prostatic enlargement pharmacological treatment by measuring symptom improvement, persistence and deterioration in real life. A prospective registry was conducted for 24 months in 5 European countries and analyzed by the European Association of Urology Research Foundation. Previously untreated and treated patients were enrolled to the registry in both primary care and urology referral centers