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0% vs 13.2%; P .05). No graft loss occurred in the drain group. Prophylactic drainage after pancreas transplant may be helpful for reduction in the infection rate after reoperation. The risks of drain placement should be weighed against those of drain avoidance. Prophylactic drainage after pancreas transplant may be helpful for reduction in the infection rate after reoperation. The risks of drain placement should be weighed against those of drain avoidance. Ischemia-reperfusion injury is correlated with a substantial inflammat