https://www.selleckchem.com/pr....oducts/abc294640.htm
Finally, a docking study was also performed using MTB DNA Gyrase (PDB ID 5BS8) for the significantly active compound 8a to know the exact binding pattern within the active site of the target enzyme.Indole-benzimidazoles have recently gained attention due to their antiproliferative and antiestrogenic effects. However, their structural similarities and molecular mechanisms shared with selective estrogen receptor modulators (SERMs) have not yet been investigated. In this study, we synthesized novel ethylsulfonyl indole-benzimidazole deri
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