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Anogenital distance (AGD), the exact distance through the rectum into the genitals, is a marker of normal genital development. AGD along with other biometric variables of external female genitalia are essential as ultrasonographic markers that can determine fetal sex in the 1st trimester. Neural pipe flaws tend to be among the commonest congenital malformations for the nervous system, with anencephaly being many severe defect. Feminine genitalia development and their connection