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BACKGROUND Hemolytic uremic syndrome (HUS) is a multisystemic condition. In a nationwide study, we characterized the incidence, clinical course, and prognosis of HUS brought on by Shiga toxin (Stx)-producing Escherichia coli (STEC) strains with focus on risk elements, disease seriousness, and lasting result. PRACTICES The data on pediatric HUS clients from 2000 to 2016 had been collected through the health files. STEC isolates from fecal countries of HUS and non-HUS patients had been