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We searched the classic medical reference publications for the 9th to nineteenth centuries for the terms 'polluted atmosphere' and 'pandemic', and now we searched 4 databases (PubMed, Google Scholar, Science Direct, and Scopus) with the keywords 'COVID-19', 'pandemic', 'history', and 'prevention programs'. The outcome had been gathered and put through content evaluation. Through the standpoint of conventional Iranian physicians, condition prevention is mainly feasible by preventing pathogeni