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All these results indicated that P. plecoglossicida could cause systemic diseases with typical clinical sighs to barramundi and would be an alarming pathogen to barramundi industry. To evaluate whether subjects with diabetes hospitalized for Coronavirus disease-19 (Covid-19) represent a subgroup of patients with high-risk clinical features compared to patients with diabetes without Covid-19. In this case-control study 79 patients with type 2 diabetes out of 354 adults hospitalized for Covid-19 and 158 controls with type 2 diabetes but with