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Drug bound to a target ended up being assessed in peripheral blood mononuclear cells (PBMC). All four dogs demonstrated reduction in lesions and cPDAI score during the first two weeks of treatment. Three dogs carried on to improve and sustained near total remission by 20 weeks, from which point three answers were considered "good" and one "fair". Final day-to-day dosages had been within the range 17-33mg/kg. Anti-DSC-1 IgG titre decreased considerably in one puppy, en
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