https://www.selleckchem.com/pr....oducts/gsk2256098.ht
This mechanism supported a higher in vivo response. Indeed, immunoliposomes promoted full tumor regression in 20% of mice and increased in 1 month the survival rate. This formulation was the only treatment able to induce significant (p 0.01) increase of activated tumor specific cytotoxic T lymphocytes at the tumor site. PD-L1 targeted liposomes encapsulating Dox have proved to be a rational combination able to enhance the modulation of the immune system by blocking PD-L1 and selectively internalizing Dox, thus successfully provi
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