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ys after the surgery, and incidence of serious adverse events. The results of this randomised controlled trial will provide valuable information for the standardisation of management of anticoagulants in patients scheduled to undergo colorectal polypectomy. UMIN-CTR UMIN000023720 . Registered on 22 August 2016. UMIN-CTR UMIN000023720 . Registered on 22 August 2016. A skin flap is one of the most critical surgical techniques for the restoration of cutaneous defects. However, the distal necrosis of the skin flap severely restricts