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Consequently, their particular programs and transformations have received significant attention in the past few decades. The solitary, two fold, triple and quadruple cleavage of halodifluoromethyl compounds and various deconstructive settings of trifluoromethyl-containing substances could create a number of synthons to get ready much more valuable items. Herein, we summarize the most important accomplishments in this field with an intriguing give attention