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Major complications occurred in 4/98 (4%) of lung biopsies (four pneumothoraxes requiring chest tube placement). Percutaneous CT-guided biopsy is an alternative to endoscopic or surgical biopsy for the diagnosis of persistent consolidation with a low risk of severe complication. Percutaneous CT-guided biopsy is an alternative to endoscopic or surgical biopsy for the diagnosis of persistent consolidation with a low risk of severe complication. Intervention planners need to be sufficiently cognisant of the health system lan