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We recruited 478 successive premenopausal adult females without any indicator of gynecologic or psychiatric illness, who had been going to an outpatient functional bowel disorders clinic. Patients completed a Rome III questionnaire, psychological assessment feces form, and a 10-point Likert scale for irregularity, diarrhea, bloating, and abdominal pain. These patients underwent physiological tests, anorectal manometry, and colonic transportation time and had been