https://akti-1-2.com/researchi....ng-the-particular-ba
The upstream regulating pathways as well as the downstream components of miR-34c in AD remain to be examined. The expression of miR-34c ended up being recognized by RT-qPCR in oxidative stressed neurons, hippocampus of SAMP8 mice, or serum of patients with amnestic mild cognitive impairment (aMCI). Dual luciferase assay ended up being done to confirm the binding sites of miR-34c in its target mRNA. The Morris water maze (MWM) was utilized to evaluate understanding and memory in