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Recently, lysine acetylation (Kac) and lysine succinylation (Ksuc) have been identified in microbial proteins with diverse biological and pathological functions. The Ksuc of P. gingivalis ATCC 33277 is characterized inside our previous work, and here, we report the systematic analysis of Kac as well as its crosstalk with Ksuc in this bacterium. A variety of the affinity enrichment because of the acetyl-lysine antibody with extremely painful