https://www.selleckchem.com/pr....oducts/ag-120-Ivosid
PVT1 silencing. Overall, we provide first evidence that PVT1 was involved in signaling a genome-wide androgen-dependent transcriptional repressive program of tumor suppressor protein-coding genes in prostate cancer cells. Identification of transcriptional inhibition of tumor suppressor genes by PVT1 highlights the pathway to the investigation of mechanisms that lie behind the oncogenic role of PVT1 in cancer. Video Abstract. Overall, we provide first evidence that PVT1 was involved in signaling a genome-wide androgen-dependent
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