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There aren't any earlier researches of povidone iodine (PVP-I) against SARS-CoV-2. This study examined nasal and oral antiseptic formulations of PVP-I for virucidal task against SARS-CoV-2. This is the very first report from the efficacy of PVP-I from the virus that causes COVID-19. Povidone iodine nasal antiseptic formulations and PVP-I oral rinse antiseptic formulations from 1% to 5% levels also settings had been studied for virucidal effectiveness aga