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Clients progressing by PSA after 6 wk of treatment could benefit from an extremely early therapy switch decision. PSA flare-up during LuPSMA treatment is very unusual. Potential researches are now warranted to verify our results and possibly notify clinicians early in the day regarding the effectiveness of LuPSMA. Copyright © 2020 because of the Society of Nuclear Medicine and Molecular Imaging, Inc.The accuracy of lutetium-177 (177Lu) radiotracer focus measurements using qu