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For this specific purpose, uninfected mosquitoes and mosquitoes carrying a 6 day old Plasmodium relictum disease (early oocyst stages) were allowed to feed either on a drug-treated or an untreated host in a fully factorial test. This protocol permitted us to sidestep the gametocyte stages and establishatable to human malaria, the potential epidemiological and evolutionary consequences associated with current preventive use of sulfadoxine-pyrimethamine in malaria-endemic na
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