https://www.selleckchem.com/pr....oducts/ch7233163.htm
We investigated the cost-effectiveness of three sequential prenatal cystic fibrosis (CF) carrier screening strategies genotyping both partners, genotyping one partner then sequencing the second, and sequencing both partners. A decision-analytic model compared the strategies in a theoretical cohort of four million pregnant couples in the US population and five racial/ethnic sub-populations. Inputs were obtained from literature and varied in sensitivity analysis. Outcomes included cost per quality-adjusted life year (QALY), missed carri