https://www.selleckchem.com/pr....oducts/srt2104-gsk22
Hexabromocyclododecanes (HBCDs), widely used brominated flame retardants, easily accumulate in aquatic organisms such as Macrophthalmus japonicus crabs, which inhabit tidal flat sediments. To analyze the effects of HBCD exposure in chitin-formed exoskeleton, we investigated molecular responses of chitin-related genes as well as physical changes of the exoskeletal surface form as a new biological end-point on M. japonicus. The expression patterns of chitin biosynthesis-, modification-, and degradation-related genes in the gill