https://www.selleckchem.com/pr....oducts/eidd-2801.htm
Klinefelter syndrome (KS) is the most common sex aneuploidy in men. Affected males have hypogonadism, and, as a result, face an increased risk for osteoporosis and fractures. Androgen therapy is standard in adolescents and adults with KS but has not been used earlier in childhood. To determine the effects of androgen treatment on bone mass in children with KS. Randomized, double-blind, placebo-controlled clinical trial of oxandrolone (OX; 0.06 mg/kg daily; n = 38) versus placebo (PL; n = 4 for 2 years in boys with KS (ages 4-12 year