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Electroencephalograms (EEG) performed for 32.9% of the patients (n = 5 were abnormal for 74% (n = 37). We described the world's biggest case series of ceftriaxone-induced serious CNS ADRs. Explorations (plasma concentrations, EEG) are contributive to confirm the ceftriaxone toxicity-induced. Clinicians may be cautious with the use of ceftriaxone, especially in the older age or renal impairment population.The quantification of blood flow velocity in the human conjunctiva is clinically essential for assessing microvascular he