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Effective suicide prevention is hindered by a limited understanding of the neurobiology leading to suicide. We aimed to examine the association between changes in the experience of pain and disturbances in sleep quantity and quality in patients with elevated risk for suicide. Three groups of adult depressed individuals, including patients following a recent suicide attempt ( = 79), patients experiencing current suicidal ideation ( = 131), and patients experiencing depression but no suicidal ideation or behavior in at least 6 months (