https://www.selleckchem.com/pr....oducts/alantolactone
Endothelial dysfunction (ED) contributes to the high incidence of cardiovascular events in hemodialysis patients. Syndecan-1 in the endothelial glycocalyx can be shed into the circulation serving as a biomarker for ED. As sodium is a trigger for glycocalyx shedding, we now tested whether hemodialysis with higher dialysate sodium concentrations is associated with more syndecan-1 shedding compared with standard hemodialysis (SHD). In this cross-over study in 29 patients, plasma syndecan-1 was repeatedly measured during SHD and durin
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