https://her2-signaling.com/ind....ex.php/parotid-human
Where multi-specificity is challenging with an antibody format that is susceptible to mis-pairing between chains, multiple FN3 domain names into the fibronectin assembly already connect to a large number of particles. As such, several monobodies engineered for interaction with therapeutic targets are increasingly being combined in an equivalent beads-on-a-string system which improves both efficacy and pharmacokinetics. Additionally, full length fibronectin is able to