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The superiority of anatomic resection (AR) over non-anatomic resection (NAR) for very early-stage hepatocellular carcinoma (HCC) has remained a topic of debate. Thus, this study aimed to compare the prognosis after AR and NAR for single HCC less than 2cm in diameter. Consecutive patients with single HCC of diameter less than 2cm who underwent curative hepatectomy between 1997 and 2017 were included in this retrospective study. In total, 159 patients were included in this study. Of these, 52 patients underwent AR (AR group) and 107 patien