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ADHD in Adults Treatment ADHD is associated with significant difficulties in social and academic functioning. Adults with ADHD are at a higher risk of developing anxiety disorders, depression, and substance abuse. Medications that improve core ADHD symptoms appear to be effective by increasing the availability of neurotransmitters that regulate the ability to focus and impulsivity. Trials of medication are conducted to determine which medication is most effective and at what dosages. Medication Treatments that are quick, such as medication can help improve AD