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Non Stimulant and Stimulant ADHD Medications The medication is an essential component of the ADHD treatment strategy. However, choosing the right one is an extended process, and it is dependent on the medical history, genetics, and experienced adverse effects. Stimulant drugs such as methylphenidate or amphetamine stimulate certain brain chemicals that help people focus and manage their impulses. They also help reduce hyperactivity. Many people with ADHD take these medications as their first option. Strattera S