https://www.selleckchem.com/pr....oducts/d-lin-mc3-dma
We aimed to assess the effects of safinamide on depression, motor symptoms, and the serotonin syndrome related to its co-administration with antidepressants in patients with Parkinson's disease (PD). We retrospectively analyzed the data of patients at 1 and 3 months of follow-up compared to baseline. = 82 (safinamide 50 mg = 22, 100 mg = 60, with antidepressants = 44). First, we found improvement in depression (Hamilton Depression Rating Scale -6 ± 5.10 at 1 month and -7.27 ± 5.10 at 3 months, 0.0001; Patient Global Impressio