Causes of Truck Crash Accidents If a truck crashes, the driver may be at fault, but there are many other factors that could cause an accident. Driver fatigue, impaired driving and trucks that carry dangerous cargo are some of the most frequently cited reasons for truck crashes. The companies that make these equipment may also be held accountable for injuries. In any case medical attention should be sought out as soon as possible, and you should consult your primary care physician if you have any injuries. Document the accident and share infor