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esented with pneumonia more frequently than those with single B. pertussis infection. Helicobacter pylori eradication therapy may lead to the perturbation of gut microbiota. We aim to investigate the impact of probiotics on eradication rate and gut microbiota during eradication therapy. A total of 162 patients receiving bismuth quadruple therapy were enrolled and randomly assigned to groups given probiotics (n = 83) or placebo (n = 79) for 4weeks. Fecal samples were collected before treatment and 2, 4, 6, and 8weeks after eradication t
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