https://www.selleckchem.com/pr....oducts/pqr309-bimira
Combined treatment of either SK-N-B-E(2) or IMR-32 cells with ISLQ and the anticancer agent cisplatin resulted in loss of cell viability that was greater than that induced by cisplatin alone. This study provides proof-of-principle that ISLQ is a potent cytotoxin for MYCN-amplified human NB cells. This is an important first step in rationalizing the further study of ISLQ as a potential adjunct therapy for high-risk NB. © 2019 The Author(s).Microglia are an essential component of the neurogenic niche in the adult hippocampus an
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