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Compared to patients without PVT, a significantly higher proportion of patients with PVT had variceal bleeding (47.33% vs 19.63%; P less then .001) and patients with PVT had a significantly higher median serum level of D-dimer (2.07 vs 1.25; P less then .001). Splenectomy and endoscopic sclerotherapy were independent risk factors for PVT in patients with cirrhosis and AD. The 1-year mortality rate did not differ significantly between patients with vs without PVT. CONCLUSIONS In an analysis of data from 2826 patients with cirrhosis, a significantly