https://www.selleckchem.com/pr....oducts/rocilinostat-
Salvionolic acid B, a CD36 inhibitor and a CD36 inhibitor antibody reduced oxLDL-induced MΦMP by 67% and 60%, respectively. Caspase 3/7 inhibition reduced MΦMP release by 52% (P less then 0.01) and caspase 3/7 activation increased MΦMP production by 208% (P less then 0.01). Mevastatin pretreatment (10 µM) decreased oxLDL-induced caspase 3/7 activation and attenuated oxLDL-stimulated MΦMP production and tissue factor content by 60% (P less then 0.01) and 43% (P less then 0.05), respectively. Conclusions OxLDL induces the pr