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In particular, the role of reactive oxygen species (ROS) and NADPH oxidase (Nox) regarding the deleterious outcomes of NE on endothelial cell function haven't been completely elucidated. Therefore, we investigated the effects of NE on ROS production in rat lung microvascular endothelial cells (RLMEC) and its own contribution to cellular death. RLMEC were treated with NE (5 ng/mL) every day and night and ROS production had been evaluated by CellROX and DCFDA fluorescence. Nox act
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